Heartbreak for Robert De Niro, 75, as the actor splits with wife Grace

Robert De Niro has split from his wife Grace Hightower after 21 years of marriage.

The 75-year-old Casino star and his 63-year-old wife Grace ‘are no longer living together’ according reports in Page Six.

The long-term couple are expected to ‘announce their breakup publicly in the coming weeks,’ alleged the publication.

All by myself: De Niro was seen solo at a New York City event on Monday (pictured)

It  is not the first split for the couple, who were wed in 1997, before Robert filed for divorce two years into their union however the arrangement was never finalised.

Robert and Grace eventually reunited, renewing their marriage vows in 2004.

The actor is notoriously private about his relationship with Grace but the pair are outspoken about their belief that their son Elliot’s autism is linked to vaccinations.

Explaining how Grace believes the his son ‘changed overnight’ after being vaccinated as a child, Robert told Today in 2017: ‘The vaccines are dangerous to certain people who are more susceptible…

‘Nobody seems to want to address that, or they say they’ve addressed it and it’s a closed issue but it doesn’t seem to be.’

‘There are many people who will come out and say I saw my kid change overnight. I saw what happened, I should have done something and I didn’t. There’s more to this than meets the eye, believe me.’

he Meet The Parents actor had previously been married to actress Diahnne Abbott, from 1976 to 1988.

The pair had a son, Raphael, in 1976 while the Oscar-winning actor adopted Abbott’s daughter Drena from a previous relationship.

The Mean Streets star also has two children with ex Toukie Smith, twin boys Aaron and Julian.